D-mannose prevents the adhesion of bacteria (uropathogenic strains of Escherichia coli, Pseudomonas aeruginosa, Shigella, Leishmania, Mycobacteria, etc.) to the surface of the tissue, thereby helping to prevent recurrent urinary tract infections. Clinical studies have confirmed the high efficacy and safety of the use of D-mannose and concomitantly acting substances (e.g. cranberry anthocyanins) in the treatment of cystitis and other bladder infections.

It is known that the composition of the gut microbiota can influence the health of distant body organs. It is believed that most bacterial urinary tract infections originate in the gut, followed by colonization of the urethra and ascendance of the pathogen to the bladder.

Inulin is a soluble fiber that occurs in more than 36,000 plant species as a reserve polysaccharide. It functions as a prebiotic and has an excellent effect on regulating the intestinal microflora by stimulating the growth of beneficial bacteria. In addition, inulin shows other excellent health effects by suppressing the expression of inflammatory factors or improving the absorption of minerals.

According to a 2009 study, cranberries (Canadian cranberry, large-fruited cranberry, Vaccinium macrocarpon) are effective in vitro and in vivo in preventing urinary tract infections. They likely act by inhibiting the adhesion of uropathogens (e.g., uropathogenic E. coli) to the urinary tract wall, thereby disrupting colonization and subsequent infection. Evidence suggests that proanthocyanidins contained in cranberries are potent anti-adherent compounds

Results from a 2014 study suggest that C. pepo pumpkin seed oil extracts are effective in urinary disorders such as OAB (Overactive Bladder Syndrome).

Magnesium relieves cramps and works synergistically with the other ingredients in the product to help with urinary tract infections.

It contributes to normal muscle function, normal mental activity and helps reduce fatigue and exhaustion.

Vitamin D plays a role in immune responses and reduces the risk of many chronic diseases. Vitamin D3 deficiency is a problem for adults and children in most countries around the world. According to a 2020 study, vitamin D3 deficiency is associated with susceptibility to urinary tract infections.

Zinc deficiency can increase the risk of infectious diseases. According to a 2019 study, zinc levels are a risk factor for recurrent urinary tract infections.